Assess Your Cardiovascular Health Risk:

Advanced Lipid Markers with Optional Genomic Markers

Available to everyone throughout UK, Ireland and rest of Europe, order your test kit below.

Why Use the CV Health Plus Genomics Profile?

CV Health Plus Genomics is a cardiovascular risk assessment that analyzes lipid biomarkers and genomic risk factors associated with cardiovascular disease (CVD) and helps assess your risk for heart disease. Traditional lipid markers (such as LDL cholesterol, HDL cholesterol and triglycerides) while informative, do not fully account for individual cardiovascular risk

The CV Health Profile assesses a combination of standard lipid markers and advanced biomarkers that provide information on cholesterol metabolism, inflammation, and insulin resistance.

The CV Health Plus Genomics Profile analyzes for the above in addition to DNA mutations known as single nucleotide polymorphisms (SNPs) in four select genes related to cardiovascular health and blood clotting. With this genomic insight and biomarker information, it is possible to create highly personalized, targeted interventions that address specific metabolic areas to help minimize risk and support improved cardiovascular health.

Who might benefit from CV Health with/without genomics:

CV Health Plus Genomics can help identify individuals at risk for cardiovascular disease and allow for monitoring of previously abnormal results.

CV Health Profile may be appropriate for you if any of the following apply:

• You have a family history of heart disease, stroke or high cholesterol
• High cholesterol has been detected in routine blood tests
• You have cardiovascular disease, early-onset or otherwise
• You have abnormal serum lipids
• You suffer from obesity and/or diabetes
• You are a smoker
• You have a sedentary lifestyle or are physically inactive
• You would like to check the impact of your diet on your blood lipid markers
• You would like this information to help direct your dietary choices

About the CV Health Plus Genomics Profile

Colour-coded graphics, the CV Health Plus Genomics report synthesizes test results into an easy-to-interpret reporting format. Genomic results are reported with accompanying information on health implications and treatment options.

CV Health Plus Genomics offers an innovative assessment featuring an advanced lipid profile using Nuclear Magnetic Resonance (NMR) fractionation technology, inflammatory biomarkers, and a novel Insulin Resistance Score. In addition, this profile includes analysis for single nucleotide polymorphisms (SNPs) in four select genes related to cardiovascular health and blood coagulation.

Both Cardiovascular Health profiles evaluate:

• Lipid Markers
  • LDL, HDL, Total Cholesterol, Triglycerides
  • LDL – Particle Number and Size
  • HDL – Particle Number and Size
  • Lipopreotein(a) - Lp(a)
• Independent Risk Factors
  • High Sensitivity CRP (hs-CRP)
  • Lp-PLA2 (PLAC)
  • Fibrinogen
  • Homocysteine
• Insulin Resistance Score by Lipid Fractionation, combining:
  • Small LDL – Particle Number
  • LDL Size
  • Large VLDL – Particle Number
  • VLDL Size
  • Large HDL – Particle Number
  • HDL Size

CV Health Plus Genomics™ offers all biomarkers listed above plus the additional analyses of single nucleotide polymorphisms (SNPs) in four select genes related to cardiovascular health and blood coagulation:

• APOE – plays a key role in lipid metabolism by removing dietary cholesterol (chylomicrons and VLDL) from the bloodstream
• MTHFR – a key enzyme in folate metabolism, a required cofactor in the re-methylation of homocysteine to methionine
• Factor II (Prothrombin) – converts to active form, thrombin, forming the essential part of a blood clot
• Factor V (Leiden) – combines with Factor X to convert prothrombin to thrombin

What Advantages Do the CV Health Profiles Offer Compared to Other Diagnostics?

Traditionally assessed risk factors do not fully account for the development of cardiovascular disease, the number one cause of death in the US. The CV Health profiles offer a comprehensive evaluation featuring an advanced lipid profile that utilizes Nuclear Magnetic Resonance (NMR) fractionation technology, inflammatory markers, and a novel Insulin Resistance Score. These advanced biomarkers provide insight into metabolic areas associated with CVD risk, significantly increasing diagnostic yield. In addition, the genomics option provides insight into genetic predispositions that may increase risk for the development of cardiovascular disease.

Test Details:

Laboratory:

• Genova Diagnostics

Test name(s):

• MET13 – CV Health™
• MET14 – CV Health Plus Genomics™

Specimen Requirements:

• CV Health™: Blood specimens required. Refer to test kit instructions for details.
• CV Health Plus Genomics™: Blood specimens and Buccal Swabs required. Refer to test kit instructions for details.

Costs - Accurate at May 2021:

Lab Analysis Fees:

• CV Health™: £240
• CV Health Plus Genomics™£500

Please note that blood draw fees and shipping are payable in addition to above test analysis fees

• Shipping Fees to send samples to laboratory:

 £12 UK; £23 other countries.

• Phlebotomy Fees: variable depending on location, clinic used etc (please contact us for further info)

Order your Test Below

Please complete details below to order a test kit for the CV Health™ or CV Health Plus Genomics™. Test kits include full instructions.  You will be invoiced for the test via email prior to test kit being sent out to you.

Technicalities

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Please request your lab tests via email.