Array 5: Cyrex Autoimmunity Test

Measures predictive autoantibodies, some of which can appear up to 10 years before clinical symptoms.

Efficiently and economically assesses possible tissue damage to multiple organs of the body.



Cyrex Array 5: Multiple Autoimmune Reactivity Screen

Cyrex Array 5: Autoimmun Reaktivität


Autoimmune Reactivity and Risk for Autoimmune Disease

Assesses multiple tissues commonly targeted by auto-antibodies, including

thyroid, joints, heart, gut, brain, pancreas, liver, ovaries, bone and others.

"Predictive antibodies" can indicate your risk 5-10 years before autoimmune disease occurs!




Cyrex Testing International


UK and Europe including Ireland, Belgium, Germany, Austria, Switzerland, France, Sweden, Slovenia, Lithuania and more, plus many other countries worldwide.


Cyrex Tests are possible almost everywhere. Just order your Cyrex Arrays and test kit online and then we'll send you your Cyrex Test Kit and Requisition Form. Have your blood draw at a phlebotomy provider in your own country/locality and we'll do the rest. How to arrange Cyrex Testing is explained in more detail here. We also offer consultations online via Zoom/Skype/Facetime, to interpet your test results and plan how to address your health complaints.


Cyrex Deutschland: Bestellungen und Bezahlung für Labortests



What is Autoimmunity?


Autoimmune disorders occur when your immune system “attacks itself”. Your body’s affected organ or tissue (eg thyroid, colon, pancreas, joints, etc) is “mistaken” for a foreign / toxic antigen (eg bacteria, toxic chemical or food antigen such as gluten). In a similar way to which you may have an allergic (immune) reaction to gluten or pollen or parabens, your body reacts and begins to mount an immune response to the particular organ or tissue that it mistakes for a foreign antigen, thus it “attacks self”. As time progresses, if the underlying causes are not addressed, the tissue/organ may become sufficiently damaged/destroyed so as to require medical attention (eg thyroid hormone for autoimmune thyroiditis, or insulin for type-1 diabetes). Your condition may then be medically defined as “autoimmune disease”.


Auto-immune disorders commonly occur in clusters, so that if you have one autoimmune disorder, you are at higher risk of developing more. In other words, they exhibit a tendency to “multiply”.


Leaky gut and food intolerances are commonly linked with auto-immunity, as foreign particles, microbes, chemicals and undigested food are able to gain entry to your bloodstream and thus circulate throughout your body. The manner in which your immune system may intervene, and the tissues/organs that may be targeted, and to what degree, depends on your unique biochemical individuality as well as multiple environmental factors. Susceptibility to various different autoimmune disorders can vary vastly between identical twins.


Many autoimmune conditions are reversible, if detected early enough (especially if identified before the “end-stage” at which medical diagnosis occurs). Once reversal has been initiated, you may be able to avoid developing other autoimmune diseases, if you address the underlying causes, triggers and mediators of your health issues. Even if your condition is not fully reversible, it might be possible to reduce medication (strictly under medical supervision) applying a functional medicine approach.


The sooner an autoimmune condition is identified, the greater chance of reversal or at least minimising tissue damage. This is why we use Cyrex Array 5: Multiple Autoimmune Reactivity Screen



What is Cyrex Array 5?


Cyrex Array 5, the “Multiple Autoimmune Reactivity Screen”, detects the presence of “auto-antibodies” in your body, by measuring both IgG and IgA antibodies to 24 different human tissues. Auto-antibody identification is the first stage in detecting auto-immune disease and the tissues/organs that are affected. Antibodies can be present in your body many years prior to a medical diagnosis and before you exhibit signs and symptoms of disease.


Array 5 is an economical and effective way to assess possible tissue damage to multiple organs of your body, and helps us assess predictive antibodies.  Elevated numbers of “predictive antibodies” are measurable as much as ten years before the clinical onset of the disease. Early detection and identification of pathogenesis, before extensive tissue damage has occurred, provides opportunity to address and arrest your autoimmune disorder, and in some cases entirely reverse the condition.

Why Use Array 5:


Under certain circumstances you may be at increased risk of developing autoimmune disorders. This test may be useful for you if you suffer from, have been diagnosed with, or suspect you have any of the following health conditions:

  • Gluten sensitivity / coeliac disease
    • Gluten produces digestive symptoms in only a minority of individuals. In the majority of people, gluten can damage non-intestinal tissue or organs such as brain, thyroid heart, skin, joints or respiratory tract.
  • Chronic intestinal permeability (“leaky gut”)
    • Leaky gut is known as the gateway for environmentally-induced autoimmune disorders.
  • Diagnosis of any autoimmune disease
    • Such individuals commonly develop further autoimmune conditions. Using the results from Array 5 can help us effectively target your health needs; in this way you may be able to avoid developing other autoimmune disorders, and potentially reduce your medication (under strict medical supervision).
  • Chronic toxin/chemical exposure
    • All of us are exposed to toxic chemicals. Even unborn foetuses when tested are found to contain multiple chemicals.
    • Some people react to the chemicals that we are exposed to, and sometimes these chemicals trigger auto-immune reactivity, and/or adversely influence our health in other ways. This may be because you have had increased exposure to chemicals, or because you are harbouring chronic infections, or have reduced detoxification capacity.
    • If you suspect you are reacting to chemicals, you may also wish to consider Cyrex Array 11: Chemical Immune Reactivity Screen, to assess the degree at which many chemicals might be triggering auto-immune reactivity and therefore proving detrimental to your health.
  • Infectious Agents including chronic infections, viruses and moulds
    • Latent infections as triggers of autoimmunity may be identified in Cyrex Array 12: Pathogen Associated Immune Reactivity Screen. If you suspect you may be harbouring a latent infection as well as possible auto-immune disorders, then you are advised to run Array 12. If Array 12 has already identified infectious agents in you, then it is possible that your immune system is mistaking parts of your body for foreign antigens, via a process known as "molecular mimicry". In this case you are advised to use Cyrex Array 5 and possibly Array 20: Blood Brain Barrier Permeability Screen, to figure out which tissues/organs are under attack, so that you can do something about it before such time as the damage becomes irreversible.
  • Any idiopathic condition (i.e. spontaneous symptom onset, often without apparent cause)


This is not a test to diagnose disease, but rather identify the presence of auto-antibodies to tissues within your body. Thus providing a window of opportunity to address, prevent deterioration of, and possibly reverse your condition.


Array 5 tests for ongoing damage to the following tissues and organs:

  • Parietal Cell + ATPase IgG + IgA Combined
  • Intrinsic Factor IgG + IgA Combined
  • ASCA + ANCA IgG + IgA Combined
  • Tropomyosin IgG + IgA Combined
  • Thyroglobulin IgG + IgA Combined
  • Thyroid Peroxidase (TPO) IgG + IgA Combined
  • 21 Hydroxylase (Adrenal Cortex) IgG + IgA Combined
  • Myocardial Peptide IgG + IgA Combined
  • Alpha-Myosin IgG + IgA Combined
  • Phospholipid IgG + IgA Combined
  • Platelet Glycoprotein IgG + IgA Combined
  • Ovary/Testis* IgG + IgA Combined
  • Fibulin IgG + IgA Combined
  • Collagen Complex IgG + IgA Combined
  • Arthritic Peptide IgG + IgA Combined
  • Osteocyte IgG + IgA Combined
  • Cytochrome P450 (Hepatocyte)
  • IgG + IgA Combined
  • Insulin + Islet Cell Antigen
  • IgG + IgA Combined
  • Glutamic Acid Decarboxylase 65 (GAD 65)
  • IgG + IgA Combined
  • Myelin Basic Protein IgG + IgA Combined
  • Asialoganglioside IgG + IgA Combined
  • Alpha + Beta Tubulin IgG + IgA Combined
  • Cerebellar IgG + IgA Combined
  • Synapsin IgG + IgA Combined


NB:  Immunosuppressant and corticosteroid drugs can reduce antibody production and distort test results eg with false negatives when results would otherwise be positive. Please contact us for more information if you are unsure when/whether to proceed with this test.

For further information, please contact us here

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Photography by Shirley Bloomfield-Davies